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Showing posts with label carbon nanotubes. Show all posts

As technology enters the close of the first decade this millennium, nanotechnology becomes increasingly more important in product development. Processors, chipsets, memory, displays and other electronics are marching toward the use of nanotech at and astonishing rate. In the U.S., we're already developing technology manufactured at the nanometer and sub-nanometer (picometer) level.

Carbon nanotubes, a high strength and versatile material composed of molecular configurations of pure carbon, may be the key to next generation technology in everything from the space elevator to high-speed processors. But outside of research, nanotech is here already. Research advocates have identified more than 400 consumer products in the U.S. labeled as "nano-based."  Some of these products, like microprocessors, pose relatively little risk to consumer, but the long term effects of other products like nano-aerosols is a bit less understood.  Additionally, the manufacturing by-products of these products are completely unregulated or monitored.

Nanotech and the production of nano-based devices create a type of pollution that is so small, it is extremely difficult to detect or contain. Researchers are afraid of the effect that nanopollution might have on humans, animals and other living organisms.

Nanoparticles are so small that they easily penetrate cells, a handy technique when geneticists attempt to modify genes when done intentionally. However, even when deliberate, the body detects foreign objects and creates phagocytes to break down invading material. Of course, if the body's phagocytes are busy digesting nanoparticles, the cells can't break down bacteria or other debris inside the body. Quantum dots, or nanoparticles used for semiconductors, are so small that they will actually pass right through cell walls -- yet we have relatively little research on what occurs when quantum dots interact with the human body.

The immunosensor can be used in clinical and medical diagnoses.It is vital to early diagnose cancer in order to improve the treatment for the patients. Nowadays, the need for reliable diagnosis tests has attracted the attention of many scientific societies in order to identify tumor markers in human serum.

Prostate specific antigen (PSA) is known as a valuable biomarker for the treatment of patients who suffer from prostate cancer. The aim of this research was to design and to produce a nanocomposite by using carbon nanotubes and ionic liquids in order to be used in the production of sensitive, repeatable, simple, and cost-effective immunosensors for the measurement of tumor markers, especially, PSA tumor marker.

Sandwich connection was used in this research in order to measure PSA. In this method, the stabilized antibody firstly entraps the related analyte (antigen), then the entrapped antigen is identified and measured with the help of the second marked antibody. Sandwich method has very high selectivity and sensitivity because it uses two similar antibodies.

At the same time with its simplicity (the lack of the need for complicated synthesis procedures), the nanocomposite synthesized in this research increased the sensitivity in the process in comparison with other methods reported in the references due to its increase in the surface. The other advantage in the designing and production of immunosensors is that it does not need surface blocking materials such as bull albumin serum. The reduction in incubation time between antibody and antigen, and selectivity are among other characteristics of this immunosensor.

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